The metabolic health gap in women's care
Women are disproportionately affected by metabolic conditions — yet remain underrepresented in clinical research.
Hormonal fluctuations across the lifespan significantly impact glucose tolerance, energy metabolism, and inflammatory markers. PCOS, gestational diabetes, Alzheimer's, and perimenopause all share a common thread: insulin resistance and poor glucose control. But the tools to understand and optimize metabolic health have been locked away behind medical gatekeeping.
Women achieve measurable improvements in weight, energy & symptom management through glucose control
We analyzed cohorts of up to 1743 users and over 66,000 logged symptoms. Our research reveals something remarkable: when women can see how their bodies respond in real time, they don't just feel better — they achieve clinically meaningful improvements in weight, energy, and symptom management.
Analysis period: Q1 2025 – Q1 2026. Data sources: User-reported symptoms via Hello Inside app (Metabolic Health Assessment + Daily Journal). Overall dataset: 1,743 users, 66,203 logged symptoms. Symptom improvement cohort: 1,295 users active on the platform for at least 90 days. Weight cohort: 1,189 users tracked consistently across full-year 2025; among women who lost weight (n=502), average loss was 4.15 kg with BMI shifting from 26.1 to 24.6. Analysis method: Kendall's Tau correlation for trend analysis over 90-day periods. Improvement definition: any downward trend in symptom severity (1–3 scale). Hello Inside holds EQUAL CARE® certification for sex & gender-aware Digital Preventative Health (05/2025). Full references available in the complete report.
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"We've lost touch with our bodies. It's time to reconnect & reclaim our power."
Mario Aichlseder, Co-Founder & CEO of Hello Inside
This white paper is proof that our mission works.
The findings at a glance
4 kg average weight loss in 3 months
Average BMI 26.1 -> 24.6 across 2025 through metabolic optimization, not restrictive dieting.
76.5% Improved at least one symptom
Within 90 days of using Hello Inside. n=1,082 users analyzed.
+23.7pp CGM advantage
over non-CGM: Real-time glucose feedback drives significantly more behavior change.
80.3% Improvement with cycle tracking
Women tracking symptoms + menstruation see even stronger outcomes. (n=317).
9.7 days = Fastest symptom improvement
Sleep disturbances improved in as little as 10 days. Energy in 9.7.
91% Reduced cravings in menopause
Self-reported by menopausal women using glucose insights. (n=89).
Your metabolism drives energy, mood, weight, focus, sleep, and long-term vitality. Less than one-third of normal-weight adults are metabolically healthy — decreasing to just 8% for overweight and 0.5% for obese individuals. The most frequently reported symptoms among Hello Inside users were stress, lack of energy, bloating, sleep disturbances, and cravings. Lacking energy showed the fastest improvement trajectory across the cohort, with users reporting measurable relief in under 10 days.
*Based on analysis of 1,082 women tracking symptoms over 90 days. Improvement defined as any downward trend in symptom severity (1-3 scale).
Macro trends driving the opportunity
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GLP-1 Therapy Boom
Many patients regain weight after discontinuing GLP-1s because underlying habits haven't changed. Parallel lifestyle interventions through CGM can stabilize outcomes.
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Wearables Gap
A critical gap exists in glucose integration with mainstream wearables. Hello Inside provides the women-first metabolic intelligence layer with Apple Health, Garmin, and Oura integrations.
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Preventative Health Crisis
PCOS, Type 2 Diabetes, gestational diabetes, and Alzheimer's share a common thread — insulin resistance. Early intervention could save billions in treatment costs.
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FemTech Investment Wave
Significant investment is flooding into FemTech as regulatory focus on gender health equity creates tailwinds for validated, women-specific solutions.
’’I finally understand why my cravings get worse before my period. Seeing the glucose data alongside my cycle was a total revelation.’’
’’Adding a salad before my meal and taking a 10-minute walk after eating changed everything. Small hacks, huge difference.’’
’’I used to think my afternoon crash was just part of being a working mom. Now I know it's my glucose responding to my lunch choices — and I can change it.’’
How was the clinical data collected?
How was the clinical data collected?
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What does “symptom improvement” mean in this report?
Who is included in the cohorts?
Who is included in the cohorts?
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